Cancer BiologybioRxiv
PDGFRA Defines the Mesenchymal Stem Cell Kaposi’s Sarcoma Progenitors by Enabling KSHV Oncogenesis in an Angiogenic Environment
J. Naipauer, S. Rosario, S. Gupta…·E. Mesri
The paper identifies PDGFRA+ bone marrow-derived mesenchymal stem cells as Kaposi’s sarcoma progenitors and shows pro-angiogenic conditions enable KSHV oncogenesis through epigenetic de-repression.
DOI 10.1371/journal.ppat.1008221