Author

J. Naipauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

D. Salyakina· 3 shared E. Mesri· 3 shared M. Abba· 3 shared S. Rosario· 3 shared S. Williams· 3 shared E. A. Mesri· 2 shared E. Lacunza· 2 shared O. Coso· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

D. Salyakina

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single-cell RNA sequencing identifies KSHV-infected Mesenchymal stem cell subpopulations precursors of Kaposi's Sarcoma

J. Naipauer, E. Lacunza, A. Ahuja, O. A. Coso, M. Abba, E. Mesri

The paper uses single-cell RNA sequencing to identify KSHV-infected hMSC subpopulations that exhibit features of KS progenitor cells through upregulated viral and host oncogenes in a pro-angiogenic environment.

bioRxiv · Feb 28, 2023 · PreprintMicrobiology

A non-coding RNA network involved in KSHV tumorigenesis

J. Naipauer, M. E. Garcia Sola, D. Salyakina, S. Rosario, S. Williams, O. Coso, M. C. Abba, E. A. Mesri, E. Lacunza

The paper identifies a non-coding RNA network involving lncRNAs and miRNAs that modulate KSHV tumorigenesis pathways and develops therapeutic target signatures.

bioRxiv · Mar 5, 2021Cancer Biology

RNA-sequencing analysis of a multistep and hit-and-run cell and animal model of KSHV tumorigenesis reveal the roles of mutations, CpG methylation, and viral-infection footprints in oncogenesis.

j. naipauer, S. Rosario, D. Salyakina, G. Journo, S. Williams, M. Abba, M. Shamay, E. A. Mesri

The paper uses RNA-seq and methylation analysis in a KSHV mouse model to show how viral infection and host mutations drive oncogenesis through epigenetic and genetic changes.

bioRxiv · Oct 3, 2019 · PreprintCancer Biology

PDGFRA Defines the Mesenchymal Stem Cell Kaposi’s Sarcoma Progenitors by Enabling KSHV Oncogenesis in an Angiogenic Environment

J. Naipauer, S. Rosario, S. Gupta, C. Premer, O. Mendez, M. Schlesinger, V. Ponzinibbio, V. Jain, L. Gay, R. Renne, H. L. Chan, L. Morey, D. Salyakina, M. Abba, S. Williams, , E. Mesri

The paper identifies PDGFRA+ bone marrow-derived mesenchymal stem cells as Kaposi’s sarcoma progenitors and shows pro-angiogenic conditions enable KSHV oncogenesis through epigenetic de-repression.

bioRxiv · Oct 2, 2019Cancer Biology

A major Role for Nrf2 transcription factors in cell transformation by KSHV encoded oncogenes.

D. Sapochnik, A. Raimondi, V. Medina, J. Naipauer, E. Mesri, O. Coso

This study identifies Nrf2 transcription factors as key mediators of KSHV oncogene-induced cell transformation through the vGPCR-Ga13-RhoA signaling pathway and Erk1/2 MAPK activation.

bioRxiv · Jun 21, 2019 · PreprintCancer Biology