O. Sekulovic

Multiple regulatory mechanisms control the production of CmrRST, an atypical signal transduction system in Clostridioides difficile

This study identifies multiple regulatory mechanisms controlling cmrRST expression in C. difficile, including phase variation, c-di-GMP signaling, and autoregulation by CmrR.

Phase variation of a signal transduction system controls Clostridioides difficile colony morphology, motility, and virulence

This paper identifies a phase-variable signal transduction system in C. difficile that controls colony morphology, motility, and virulence, with implications for bacterial survival and pathogenesis.