Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)
M. Ferguson, K. N. Delgado, S. McBride, I. C. Orbe, C. J. LaVake, M. J. Caimano, Q. Mendez, T. F. Moraes, A. B. Schryvers, M. A. Moody, J. D. Radolf, M. Weiner, K. L. Hawley
This paper uses the Epivolve phage display method to generate monoclonal antibodies targeting a subdominant epitope on Treponema pallidum BamA, showing opsonic activity in macrophage assays.
bioRxiv · May 13, 2023Immunology