BiophysicsbioRxiv
Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia
A. Nematbakhsh, W. Sun, P. A. Brodskiy…·M. S. Alber
This study develops a multi-scale computational model to investigate how mechanical factors regulate mitotic rounding in epithelial tissues, finding that all three factors—adhesion, cortical stiffness, and pressure—must be coordinated for robust rounding.
DOI 10.1371/journal.pcbi.1005533