Programming the lymph node immune response with Amphiphile-CpG induces potent cellular and humoral immunity following COVID-19 subunit vaccination in mice and non-human primates
L. M. Seenappa, A. Jakubowski, M. P. Steinbuck…·P. C. DeMuth
This study evaluates an AMP-CpG adjuvant in combination with SARS-CoV-2 RBD as a subunit vaccine, showing enhanced T cell and cross-reactive antibody responses in mice and NHPs.