Cell BiologybioRxiv
Mild impairment of mitochondrial function increases longevity and pathogen resistance through ATFS-1-driven activation of p38-regulated innate immunity
J. Campos, Z. Wu, P. D. Rudich…·J. Van Raamsdonk
This paper shows that mild mitochondrial dysfunction in C. elegans extends lifespan and enhances pathogen resistance via ATFS-1-driven activation of p38-regulated innate immunity.
DOI 10.15252/embr.202152964