Cancer BiologybioRxiv
Tumor-on-a-chip platform to interrogate the role of macrophages in tumor progression
Y. Bi, V. S. Shirure, R. Liu…·R. C. Fields
This study uses a tumor-on-a-chip platform to show that M1 macrophages inhibit tumor growth and angiogenesis, while M2 macrophages promote tumor migration and angiogenesis through distinct molecular mechanisms.
DOI 10.1093/intbio/zyaa017