Author

P. Greninger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Amzallag· 2 shared A. Friedman· 2 shared E. Ruppin· 2 shared L. Damon· 2 shared N. U. Nair· 2 shared A. D. Sahu· 1 shared A. Dastur· 1 shared A. Sahu· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. Amzallag

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2 papers

Recent·Most cited

A landscape of synergistic drug combinations in non-small-cell lung cancer

N. U. Nair, P. Greninger, A. Friedman, A. Amzallag, E. Cortez, A. D. Sahu, J. S. Lee, A. Dastur, R. K. Egan, E. Murchie, G. S. Crowther, J. McClanaghan, J. Boisvert, L. Damon, J. Ho, , C. H. Benes

The paper identifies synergistic drug combinations in non-small-cell lung cancer cell lines, finding that synergy often arises from sensitizing resistant models through dual pathway targeting.

bioRxiv · Jun 3, 2021 · PreprintCancer Biology

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

A. Sahu, J. Sang Lee, G. Zhang, Z. Wang, T. Tian, T. Moll, G. Kasumova, B. Miao, Z. Wei, N. U. Nair, O. Ponomarova, A. Friedman, A. Amzallag, P. Greninger, R. Egan, , E. Ruppin

The paper predicts synthetic rescue mediators of resistance to targeted and immunotherapy using tumor transcriptomics and survival data from 10,000 TCGA patients, validating predictions through experimental screens.

bioRxiv · Apr 8, 2018Cancer Biology