Author

P. J. M. Openshaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

H. Goldswain· 2 shared J. A. Hiscox· 2 shared J. K. Baillie· 2 shared J. P. Stewart· 2 shared L. Turtle· 2 shared M. G. Semple· 2 shared N. Randle· 2 shared R. Penrice-Randal· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

H. Goldswain

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintMar 30, 2021

Sequence analysis of SARS-CoV-2 in nasopharyngeal samples from patients with COVID-19 illustrates population variation and diverse phenotypes, placing the in vitro growth properties of B.1.1.7 and B.1.351 lineage viruses in context.

T. Prince, X. Dong, R. Penrice-Randal…·J. A. Hiscox

The paper analyzes SARS-CoV-2 sequence variation in patient samples and compares the in vitro growth of B.1.1.7 and B.1.351 variants to other isolates, finding no significant difference in growth for B.1.1.7.

DOI 10.1101/2021.03.30.437704

humanwhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivMar 3, 2021

Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humans

R. Penrice-Randal, H. Goldswain, T. Prince…·J. A. Hiscox

The paper identifies and quantifies SARS-CoV-2 leader-TRS-junctions in samples, showing phasic sgmRNA transcription in animal models and dysregulation in humans.

DOI 10.1093/gigascience/giac045

humanmouse

𝕏 PostBluesky