Cancer BiologybioRxiv
Nardilysin-Regulated Scission Mechanism Activates Polo-like Kinase 3 to Suppress the Development of Pancreatic Cancer
J. Fu, J. Li, C.-F. Li…·P. Chiao
The paper identifies a post-translational mechanism where Nardilysin cleaves Plk3 to generate an active form that suppresses pancreatic cancer development and metastasis.
DOI 10.1038/s41467-024-47242-3