P. J. Utz

This study shows that STING V154M mutation in non-hematopoietic cells activates autoreactive lymphocytes, leading to autoantibodies and lung inflammation in mice, mirroring SAVI in humans.

The paper develops Mal-ID, a machine learning framework using immune receptor data to diagnose diseases, detecting infections, autoimmune disorders, and vaccine responses.

The paper analyzes histone post-translational modifications in human immune cells to uncover their interactions and functional implications.

This study identifies a 93-gene signature associated with SLE through multi-cohort transcriptomic analysis, showing its clinical relevance and independence from known SLE-related signatures.

This paper establishes a protocol for dissociating cryopreserved synovial tissue to obtain viable cells with preserved transcriptomes and surface markers, enabling high-dimensional analysis of rheumatoid arthritis pathology.