PhysiologybioRxivPreprint
Toxin-mediated downregulation of absorptive ion transporters NHE3, DRA, and SGLT1 in the colon contributes to diarrhea associated with Clostridioides difficile infection.
F. C. Peritore-Galve, I. Kaji, A. Smith…·D. B. Lacy
This study shows CDI reduces NHE3, DRA, and SGLT1 in the colon, impairing ion transport and causing osmotic diarrhea.
DOI 10.1101/2022.11.12.516162