Author

P. Lucas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. Soler Palacios· 2 shared J. M. Rodriguez Frade· 2 shared K. Rosario· 2 shared M. Mellado· 2 shared N. M. Dheilly· 2 shared A. Cayuela· 1 shared A. Garcia-Rubia· 1 shared A. M. Gomez Pozo· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

B. Soler Palacios

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

mDia2 is an important mediator of MRTF-A-dependent regulation of breast cancer cell migration

I. Eder, V. Yu, J. Antonello, F. Chen, D. Gau, P. Chawla, M. Joy, P. Lucas, D. Boone, A. V. LEE, P. Roy

This study identifies mDia2 as a mediator of MRTF-A-dependent breast cancer cell migration and links MRTF activity to malignancy, suggesting it as a therapeutic target.

bioRxiv · Dec 21, 2023Cell Biology

Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain

E. M. Garcia-Cuesta, P. Martinez, K. Selvaraju, G. Ulltjärn, A. M. Gomez Pozo, G. D'Agostino, S. Gardeta, A. Quijada-Freire, P. Blanco Gabella, C. Roca, D. del Hoyo, R. Jimenez-Saiz, A. Garcia-Rubia, B. Soler Palacios, P. Lucas, , M. Mellado

This paper identifies a small molecule that modulates CXCR4 nanoclustering without affecting ligand binding, improving therapeutic potential over existing CXCR4 antagonists.

bioRxiv · Nov 19, 2023Cell Biology

Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming

B. Soler Palacios, R. Villares, P. Lucas, J. M. Rodriguez Frade, A. Cayuela, J. G. Piccirillo, D. Delgado Gestoso, C. Risco, F. Corrales, C. O. S. Sorzano, N. Martinez, J. J. Conesa, F. J. Iborra, M. Mellado

This study shows growth hormone remodels mitochondrial structure and promotes metabolic reprogramming in inflammatory macrophages.

bioRxiv · Aug 22, 2022Immunology

A world of viruses nested within parasites: Unraveling viral diversity within parasitic flatworms (Platyhelminthes)

N. M. Dheilly, Y. Blanchard, K. Rosario, P. Lucas

This study identifies 115 novel viral sequences in parasitic and free-living flatworms, revealing significant viral diversity and evolutionary dynamics during the transition to parasitism.

bioRxiv · Dec 15, 2021Microbiology

Characterization of vertically and cross-species transmitted viruses in the cestode parasite Schistocephalus solidus

M. A. Hahn, K. Rosario, P. Lucas, N. M. Dheilly

The paper identifies six novel RNA viruses in the cestode Schistocephalus solidus, showing vertical transmission for five and cross-species transmission for one.

bioRxiv · Oct 13, 2019 · PreprintMicrobiology