Author

P. Madrigal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. J. P. Huntly· 2 shared R. Asby· 2 shared A. Osnato· 1 shared A. S. M. Magee· 1 shared C. Mappereley· 1 shared C. Philippe· 1 shared D. Azazi· 1 shared D. Ortmann· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. J. P. Huntly

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model

N. Sakakini, R. Straver, D. Azazi, S. J. Horton, R. Asby, S. E. Richardson, P. Madrigal, E. E. Soilleux, R. J. M. Bashford-Rogers, J. de Ridder, B. J. P. Huntly

bioRxiv · Mar 25, 2024 · PreprintCancer Biology

Mannose metabolism inhibition sensitizes acute myeloid leukemia cells to cytarabine and FLT3 inhibitor therapy by modulating fatty acid metabolism to drive ferroptotic cell death.

K. Woodley, L. S. Dillingh, G. Giotopoulos, P. Madrigal, K. M. Rattigan, C. Philippe, V. Dembitz, A. S. M. Magee, R. Asby, L. N. van de Lagemaat, C. Mappereley, S. C. James, J. H. Prehn, K. Tzelepis, K. Rouault-Pierre, , P. Gallipoli

This study shows that inhibiting mannose metabolism sensitizes AML cells to cytarabine and FLT3 inhibitors by promoting ferroptotic cell death through fatty acid metabolism changes.

bioRxiv · May 16, 2022Cancer Biology

Epigenetic regulations follow cell cycle progression during differentiation of human pluripotent stem cells.

P. Madrigal, S. Pauklin, K. Jee Goh, R. Grandy, A. Osnato, D. Ortmann, L. Vallier, S. Brown

This study investigates epigenetic changes during the first two cell divisions of human pluripotent stem cell differentiation using synchronized cultures and identifies key regulatory mechanisms.

bioRxiv · Jun 26, 2020Cell Biology