Author

A. Osnato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

L. Vallier· 3 shared S. Brown· 3 shared D. Ortmann· 2 shared A. J. Collier· 1 shared B. T. Wesley· 1 shared C. Krueger· 1 shared D. Muraro· 1 shared K. Jee Goh· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

L. Vallier

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

A. Osnato, S. Brown, C. Krueger, S. Andrews, A. J. Collier, S. Nakanoh, M. Quiroga Londono, B. T. Wesley, D. Muraro, S. Brumm, K. Niakan, L. Vallier, D. Ortmann, P. J. Rugg-Gunn

This study shows that TGFβ signalling maintains naive human pluripotency by regulating SMAD2/3 binding and gene expression, with distinct effects compared to primed hPSCs.

bioRxiv · Jul 10, 2021Cell Biology

Epigenetic regulations follow cell cycle progression during differentiation of human pluripotent stem cells.

P. Madrigal, S. Pauklin, K. Jee Goh, R. Grandy, A. Osnato, D. Ortmann, L. Vallier, S. Brown

This study investigates epigenetic changes during the first two cell divisions of human pluripotent stem cell differentiation using synchronized cultures and identifies key regulatory mechanisms.

bioRxiv · Jun 26, 2020Cell Biology

Transcriptional networks are dynamically regulated during cell cycle progression in human Pluripotent Stem Cells

A. Osnato, S. Brown, L. Vallier

The paper shows that transcriptional networks and chromatin dynamics change during the cell cycle in human embryonic stem cells.

bioRxiv · Jun 14, 2020 · PreprintCell Biology