Breast adipose tissue-derived extracellular vesicles from women with obesity stimulate mitochondrial-induced dysregulated tumor cell metabolism
S. Liu, A. Benito-Martin, F. A. P. Vatter, S. Z. Hanif, C. Liu, P. Bhardwaj, P. Sethupathy, A. R. Farghli, P. Piloco, P. Paik, M. Mushannen, D. M. Otterburn, L. Cohen, R. Bareja, J. Krumsiek, , K. A. Brown
This study shows that extracellular vesicles from obese women's breast adipose tissue promote mitochondrial metabolism and proliferation in ER+ breast cancer cells.
bioRxiv · Feb 8, 2023 · PreprintCancer Biology