Author

P. Span

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Krupp· 1 shared A. L. McGregor· 1 shared A. Serebrenik· 1 shared A.-A. Varlet· 1 shared B. Verhalen· 1 shared D. Kim· 1 shared E. Cahir-McFarland· 1 shared E. Law· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Krupp

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

E. S. Bell, P. Shah, N. Zuela - Sopilniak, D. Kim, A.-A. Varlet, J. L. P. Morival, A. L. McGregor, P. Isermann, P. Davidson, J. J. Elacqua, J. Lakins, L. Vahdat, V. Weaver, M. B. Smolka, P. Span, J. Lammerding

This study shows that low lamin A levels in breast cancer cells increase nuclear deformability and metastatic capacity, with lower lamin A levels linked to poorer disease-free survival in human tumors.

Oncogene · Jul 27, 2022Peer-reviewedCancer Biology

Polyomavirus T-Antigen Induces APOBEC3B Expression using a LXCXE-Dependent and TP53-Independent Mechanism

G. Starrett, A. Serebrenik, P. Roelofs, B. Verhalen, J. McCann, M. Jarvis, T. Stewart, E. Law, A. Krupp, M. Jiang, J. Martens, P. Span, E. Cahir-McFarland, R. Harris

This paper shows polyomavirus T-antigen induces APOBEC3B expression via the LXCXE motif without requiring TP53 inhibition, linking RB/E2F axis activation to APOBEC3B upregulation in virus-infected cells.

bioRxiv · May 2, 2018Microbiology