Author

J. McCann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Law· 2 shared R. Harris· 2 shared A. Cristini· 1 shared A. England· 1 shared A. Krupp· 1 shared A. Serebrenik· 1 shared B. Holt· 1 shared B. Stefanovska· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

E. Law

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CNC Knitting Micro-Resolution Mosquito Bite Blocking Textiles

B. Holt, K. Oswalt, A. England, R. Murphy, I. Owens, M. Finney, N. Wong, S. Adhikari, J. McCann, J. F. Beckmann

The paper designs micro-resolution knitted textiles produced by robotic manufacturing to block mosquito bites and protect against vector-borne diseases.

bioRxiv · Apr 21, 2023 · PreprintBioengineering

R-loop homeostasis and cancer mutagenesis promoted by the DNA cytosine deaminase APOBEC3B

J. McCann, A. Cristini, E. Law, S. LEE, M. Tellier, M. Carpenter, C. Beghe, J. Kim, M. C. Jarvis, B. Stefanovska, N. A. Temiz, E. N. Bergstrom, D. Salamango, M. Brown, S. Murphy, , R. Harris

This study shows APOBEC3B regulates R-loop homeostasis and contributes to mutagenesis in cancer by binding R-loops and altering their landscape.

bioRxiv · Aug 30, 2021 · PreprintCancer Biology

Polyomavirus T-Antigen Induces APOBEC3B Expression using a LXCXE-Dependent and TP53-Independent Mechanism

G. Starrett, A. Serebrenik, P. Roelofs, B. Verhalen, J. McCann, M. Jarvis, T. Stewart, E. Law, A. Krupp, M. Jiang, J. Martens, P. Span, E. Cahir-McFarland, R. Harris

This paper shows polyomavirus T-antigen induces APOBEC3B expression via the LXCXE motif without requiring TP53 inhibition, linking RB/E2F axis activation to APOBEC3B upregulation in virus-infected cells.

bioRxiv · May 2, 2018Microbiology