Cell BiologybioRxiv
Smooth muscle-specific MMP17 (MT4-MMP) defines the intestinal ECM niche
M. Martin-Alonso, H. Lindholm, S. Iqbal…·M. J. Oudhoff
The paper identifies MMP17 as a smooth muscle-specific factor critical for intestinal epithelial repair and stem cell niche regulation through its cleavage of PERIOSTIN and activation of YAP.
DOI 10.1038/s41467-021-26904-6