Author

P. Z. Anastasiadis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

W.-H. Lin· 2 shared A. Singharoy· 1 shared D. Stein· 1 shared D. T. Hansen· 1 shared F. Craciunescu· 1 shared J. N. Sarkaria· 1 shared J. Zook· 1 shared L. Lewis-Tuffin· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

W.-H. Lin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivDec 3, 2021

A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma

W.-H. Lin, R. W. Feathers, L. M. Cooper…·P. Z. Anastasiadis

This study identifies a Syx-RhoA-Dia1-YAP/TAZ signaling axis that promotes glioblastoma growth, DNA damage, and therapy resistance, suggesting it as a therapeutic target.

DOI 10.1172/jci.insight.157491

humanbulk RNA-seq

𝕏 PostBluesky

BiochemistrybioRxivAug 26, 2021

Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma

R. J. Boyd, T. Olson, J. Zook…·P. Fromme

This study characterizes human Syx, a RhoGEF involved in glioblastoma, and performs computational simulations to elucidate its structure and allosteric regulation.

DOI 10.1096/fj.202101808rr

humanproteomics

𝕏 PostBluesky