P.-H. Hsieh

This study analyzes the temporal transcriptional response of endothelial cells to TNF, identifying two distinct phases of gene regulation and uncovering novel genes involved in the acute response.

This study identifies embryo-specific epigenetic mechanisms that reprogram CHH methylation during Arabidopsis embryogenesis, revealing distinct roles for RdDM and CMT2 pathways.

This study shows that H2A.X mutants in Arabidopsis thaliana exhibit reduced CG DNA methylation in endosperm, primarily in transposons and intergenic regions, suggesting H2A.X's role in maintaining methylation homeostasis.

This study shows that the FACT complex facilitates DME-mediated DNA demethylation at heterochromatin during Arabidopsis reproduction by enabling access to GC-rich, nucleosome-dense regions.