Cell BiologybioRxivPreprint
STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NFkB signaling
T. D. Fischer, E. N. Bunker, P.-P. Zhu…·R. J. Youle
This study shows STING activates NFkB signaling via HOIP-mediated M1 ubiquitin chains on Golgi membranes, independent of LC3B lipidation.