Author

R. A. Larson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

B. G. Debeb· 3 shared W. A. Woodward· 3 shared D. Tripathy· 2 shared E. Schlee Villodre· 2 shared J. Song· 2 shared N. T. Ueno· 2 shared S. Krishnamurthy· 2 shared X. Hu· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

B. G. Debeb

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3 papers

Recent·Most cited

In Vivo Simvastatin and Brain Radiation in a Model of HER2+ Inflammatory Breast Cancer Brain Metastasis

S. Kumar, R. A. Larson, S. Stecklein, J. Reddy, B. G. Debeb, R. A. Amos, S. M. Cologna, W. A. Woodward

This study examines if simvastatin and whole-brain radiation affect HER2+ inflammatory breast cancer brain metastases in a mouse model, finding mixed effects on micrometastases but not macrometastases.

bioRxiv · May 25, 2024 · PreprintCancer Biology

Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion

E. Schlee Villodre, X. Hu, R. A. Larson, P. Finetti, K. Gomez, W. Balema, S. R. Stecklein, G. Santiago-Sanchez, S. Krishnamurthy, J. Song, X. Su, N. T. Ueno, D. Tripathy, S. Van Laere, F. Bertucci, , B. G. Debeb

This study shows that lipocalin 2 promotes inflammatory breast cancer aggressiveness and skin invasion by enhancing proliferation, migration, and metastasis.

bioRxiv · Mar 18, 2021Cancer Biology

Decorin, a novel negative modulator of E-cadherin in inflammatory breast cancer

X. Hu, E. Schlee Villodre, R. A. Larson, O. M. Rahal, X. Wang, Y. Gong, J. Song, S. Krishnamurthy, N. T. Ueno, D. Tripathy, W. A. Woodward, B. G. Debeb

This study identifies decorin as a negative regulator of E-cadherin in inflammatory breast cancer, showing it reduces migration, invasion, and metastasis by destabilizing E-cadherin and inhibiting EGFR/ERK signaling.

bioRxiv · Jul 7, 2020Cancer Biology