Y. Gong

This study identifies low tumorous magnesium content as a driver factor of colorectal cancer by showing its impact on gene mutations, EMT activation, and cell migration through DBN1 phosphorylation.

The paper identifies two supergenes controlling tristyly in Eichhornia paniculata, with specific gene expression patterns and evolutionary age estimates supporting their role in the polymorphism.

This study uses phylogenomic analysis of Rumex species to resolve sex chromosome evolution, finding two independent origins and chromosomal rearrangements without adaptive expansion support.

This study identifies nuclear cytoophidia as regulators of Impdh2 transcriptional activity, impacting skeletal development and homeostasis through effects on endochondral ossification and osteoclast function.

This paper introduces FISH-scRACS-Seq, a method to identify and sequence single cells with specific metabolic functions, revealing a new cyclohexane-degrading enzyme system in marine bacteria.

The paper shows that NCOR1+/CD4+ T cells in tertiary lymphoid organs predict better outcomes in pancreatic ductal adenocarcinoma patients.

The paper studies Y chromosome degeneration in Rumex hastatulus by analyzing phased genome assemblies of old and new sex chromosomes, finding extensive gene loss and transposable element expansion on the Y chromosome.

The paper identifies superior AAV capsids for targeted spinal cord gene therapy in non-human primates through in vivo selection and evaluates their biodistribution and expression.

This study compares a novel VZV mRNA vaccine (ZOSAL) with Shingrix in mice and rhesus macaques, showing ZOSAL induces stronger T cell immunity and safety.

This study shows Mecp2 negatively regulates quiescence exit by activating metabolic genes and repressing proliferation genes, with nuclear receptors Rara and Nr1h3 playing a key role.

This study develops a modified occupancy model to distinguish true-presence from pseudo-presence in Amur tigers, improving occupancy estimation accuracy by accounting for territorial behavior.

This study identifies VHL mutation as a driver of CE accumulation in ccRCC through the PI3K/AKT pathway, showing that inhibiting cholesterol esterification suppresses tumor aggressiveness.

The paper shows that DNA virus components are packaged into exosomes by infected crustacean cells, which transmit apoptotic signals to suppress viral spread.

The paper identifies a mechanism in Arabidopsis thaliana that ensures asymmetric inheritance of a polarity domain during stomatal lineage cell divisions, linking cell polarity to division orientation and fate determination.

The paper provides simulated granular scaffolds with known void volume fraction (VVF) to study measurement accuracy and reveals VVF may be unreliable as a descriptor.

The paper develops a mathematical model of RhCMV placental transmission in rhesus macaques to study factors affecting congenital CMV infection risk.

The paper develops HypDB, a database of proline hydroxylation sites, and identifies functional roles and biomarkers through proteome analysis.

This study identifies a TM4SF1-positive cancer subpopulation in bladder cancer that drives intratumor heterogeneity and is associated with poor prognosis.

The paper shows pre-neoplastic stromal cells promote BRCA1-driven breast cancer by inducing epithelial proliferation and altering differentiation.

This paper investigates the evolution of the polarity protein BASL in stomatal lineage asymmetric divisions across species, finding it is eudicot-specific and reveals differences in division mechanisms across dicots.

The paper investigates the role of BASL in Arabidopsis stomatal lineage asymmetric cell divisions, showing distinct functions before and after division in regulating cell size and fate.

This study identifies miR-2 as a regulator of Caspase 2 in mud crabs, showing it suppresses WSSV infection through apoptosis induction.

This study shows that PKC-θ phosphorylates RanGAP1 to promote its sumoylation and assembly with RanBP2 and Ubc9, facilitating nuclear import of AP-1.

This study identifies NAC18.1 as a key gene controlling apple firmness and ripening, showing its functional similarity to the tomato ripening regulator NOR.

This study shows that young and undamaged recombinant mouse serum albumin (rMSA) extends the lifespan and healthspan of C57BL/6N mice by 17.6% and 20.3% respectively.

The paper identifies and characterizes a novel adipocyte population with active Wnt/β-catenin signaling that influences beige fat formation and glucose homeostasis in mice.

This paper develops an ultrasensitive biosensor to quantify SARS-CoV-2 RBD and ACE2 interactions in cells and in vitro, enabling rapid evaluation of viral mutants and drug candidates.

This study characterizes the dynamic changes in B-cell receptor repertoires of COVID-19 patients using next-generation sequencing, revealing clonotype overlap, lineage expansion, and V gene usage patterns.

This study identifies exosomal miR-224's role in maintaining hemolymph microbiota homeostasis during bacterial infection in mud crabs by modulating immune signaling pathways.