PhysiologybioRxivPreprint
Disruption of the surfactant protein A receptor SP-R210L (CD245α/MYO18Aα) alters respiratory function and iron sequestration in alveolar macrophages of aged mice
E. Yau, T. M. Umstead, R. Abdulqadir…·Z. C. Chroneos
This study shows that disrupting the SP-R210L isoform in aged mice impairs respiratory function and iron sequestration in alveolar macrophages, leading to chronic dysregulation and increased interstitial lung disease risk.
DOI 10.1101/2021.04.14.439860