PathologybioRxivPreprint
A network medicine approach to elucidate mechanisms underlying menopause-induced knee osteoarthritis
G. Gilmer, H. Iijima, N. Jackson…·F. Ambrosio
This study identifies menopause-induced cartilage degradation, senescence, and extracellular matrix disassembly, and suggests hormone therapy or senolytics may mitigate these effects.
DOI 10.1101/2023.03.02.530756