Author

N. Jackson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Ye· 4 shared L. Martinez-Sobrido· 4 shared S. R. Weiss· 2 shared A. Asthana· 1 shared A. Bukreyev· 1 shared A. C. Bean· 1 shared A. Kim· 1 shared A. R. Fehr· 1 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

C. Ye

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Multiple layers of innate immune response antagonism of SARS-CoV-2

F. Zhou, S. Periasamy, N. Jackson, W. S. Cheng, R. Soto Acosta, P. Ilinykh, C. Ye, S. Chauhan, G. Nudelman, E. Zaslavsky, S. Widen, L. Martinez-Sobrido, S. Sealfon, A. Bukreyev

This study generates twelve SARS-CoV-2 viruses with mutations in individual proteins and shows that many have interferon-antagonizing activity and immunosuppressive effects in human cells and mice, with NSP1 and NSP15 having the greatest impact.

bioRxiv · Jan 29, 2024 · PreprintMicrobiology

Activation of Protein Kinase R (PKR) Plays a Pro-Viral Role in Mammarenavirus Infected Cells

H. Witwit, R. Khafaji, A. Salaniwal, A. Kim, B. Cubitt, C. Ye, N. Jackson, S. R. Weiss, L. Martinez-Sobrido, J. C. de la Torre

This study shows that PKR activation can both restrict and enhance LCMV replication, revealing a complex role for PKR in mammarenavirus infection.

bioRxiv · Dec 5, 2023Microbiology

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling

C. J. Otter, N. Bracci, N. A. Parenti, C. Ye, T. Li Hui, A. Asthana, J. J. Pfannenstiel, N. Jackson, A. R. Fehr, R. H. Silverman, N. A. Cohen, L. Martinez-Sobrido, S. R. Weiss

This study shows that SARS-CoV-2 nsp15 inhibits dsRNA-induced antiviral signaling, which is necessary for viral replication in nasal epithelial cultures.

bioRxiv · Nov 15, 2023Microbiology

The SARS-CoV-2 Spike is a virulence determinant and plays a major role on the attenuated phenotype of Omicron virus in a feline model of infection

M. Martins, M. Nooruzzaman, J. L. Cunningham, C. Ye, L. C. Caserta, N. Jackson, L. Martinez-Sobrido, Y. Fang, D. G. Diel

This study shows the Omicron BA.1 Spike protein reduces SARS-CoV-2 virulence in a feline model by impairing viral spread and causing less severe disease.

bioRxiv · Oct 9, 2023Microbiology

A network medicine approach to elucidate mechanisms underlying menopause-induced knee osteoarthritis

G. Gilmer, H. Iijima, N. Jackson, Z. Hettinger, A. C. Bean, J. Bergmann, C. Evans, R. C. Thurston, F. Ambrosio

This study identifies menopause-induced cartilage degradation, senescence, and extracellular matrix disassembly, and suggests hormone therapy or senolytics may mitigate these effects.

bioRxiv · Mar 2, 2023 · PreprintPathology

Protection from Omicron and other VOCs by Bivalent S-Trimer COVID-19 Vaccine

D. Su, X. Li, X. Huang, C. He, C. Zeng, Q. Wang, Z. Mu, W. Qin, D. Ambrosino, G. Siber, R. Clemens, J. G. Liang, P. Liang, N. Jackson, R. Xu

This study develops a bivalent S-Trimer vaccine combining ancestral and Omicron S-proteins, showing enhanced neutralizing antibody responses against VOCs.

bioRxiv · May 3, 2022 · PreprintImmunology

VETA: a Matlab toolbox for the collection and analysis of electromyography combined with transcranial magnetic stimulation

N. Jackson, I. Greenhouse

VETA is a MATLAB toolbox that integrates EMG and TMS data collection, visualization, and analysis, addressing the lack of standardized tools for this combination.

bioRxiv · Apr 16, 2019Physiology