Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self
K. Geiger, M. Manoharan, R. Coombs, C.-s. Park, A. Lee, N. Shastri, E. Robey, L. Coscoy
This study shows that MCMV downregulates ERAAP, leading to self-peptide presentation and an unconventional T cell response that reduces viral load.
bioRxiv · Aug 23, 2022Immunology