E. Robey

The promiscuous development of an unconventional Qa1b-restricted T cell population

The paper identifies a CD8 T cell population, QFL T cells, restricted to MHC-E that develops independently of classical MHC I and requires Qa1b for agonist selection and functionality.

Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self

This study shows that MCMV downregulates ERAAP, leading to self-peptide presentation and an unconventional T cell response that reduces viral load.