Author

M. Manoharan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

A. Chaudhuri· 1 shared A. Lee· 1 shared A. Ramesh· 1 shared A. Srivastava· 1 shared C. M. Magdalene· 1 shared C.-s. Park· 1 shared E. Robey· 1 shared K. Bhojak· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Chaudhuri

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2 papers

Recent·Most cited

Murine cytomegalovirus downregulates ERAAP and induces an unconventional T cell response to self

K. Geiger, M. Manoharan, R. Coombs, C.-s. Park, A. Lee, N. Shastri, E. Robey, L. Coscoy

This study shows that MCMV downregulates ERAAP, leading to self-peptide presentation and an unconventional T cell response that reduces viral load.

bioRxiv · Aug 23, 2022Immunology

Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

S. Mahajan, K. Bhojak, V. Kode, C. M. Magdalene, M. Manoharan, K. Lee, A. Ramesh, S. H. V, A. Srivastava, R. Sathian, P. Kumar, T. Khan, P. Chakraborty, A. Chaudhuri

This study identifies immunodominant T-cell epitopes in SARS-CoV-2 spike antigen and shows pre-existing T-cell immunity in unexposed individuals, suggesting prior exposure to common viruses like Influenza and CMV.

bioRxiv · Nov 3, 2020Immunology