Development of robust antiviral assays using relevant apical-out human airway organoids
J.-H. Lee, J. C. LeCher, E. Parigoris, N. Shinagawa, J. Sentosa, C. Manfredi, S. L. Goh, R. De, S. Tao, K. Zandi, F. Amblard, E. J. Sorscher, J. R. Spence, R. Tirouvanziam, R. F. Schinazi, S. Takayama
This paper develops AORBs, a high-throughput human airway organoid system, to robustly assess antiviral efficacy against SARS-CoV-2 with high throughput and clinical relevance.
bioRxiv · Jan 2, 2024 · PreprintBioengineering