Author

A. Piralla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Assay:proteomics· 3 Research Focus:benchmarking· 1 Organism:mouse· 1

Frequent Co-Authors

F. Baldanti· 6 shared E. Percivalle· 4 shared H. Marcotte· 4 shared I. Cassaniti· 4 shared L. Calzolai· 4 shared F. Bertoglio· 3 shared H. Abolhassani· 3 shared J. C. Sammartino· 3 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersImmunology

F. Baldanti

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6 papers

Recent·Most cited

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages

H. Marcotte, Y. Cao, F. Zuo, L. Simonelli, J. C. Sammartino, M. Pedotti, R. Sun, I. Cassaniti, M. Hagbom, A. Piralla, J. Yang, L. Du, E. Percivalle, F. Bertoglio, M. Schubert, , Q. Pan-Hammarstrom

Engineered dimeric and secretory IgA1 neutralized Omicron variants with higher potency than parental IgG.

Proceedings of the National Academy of Sciences · Jan 9, 2024Peer-reviewedMicrobiology

Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2

F. Bianchini, V. Crivelli, M. E. Abernathy, C. Guerra, M. Palus, J. Muri, H. Marcotte, A. Piralla, M. Pedotti, R. De, L. Simonelli, M. Matkovic, C. Toscano, M. Biggiogero, V. Calvaruso, , Ru

The paper identifies broadly cross-reactive neutralizing antibodies against SARS-CoV-2 variants using coldspot-guided antibody discovery.

bioRxiv · Nov 24, 2022 · PreprintImmunology

Immunity to SARS-CoV-2 up to 15 months after infection

H. Marcotte, A. Piralla, F. Zuo, L. Du, I. Cassaniti, H. Wan, M. Kumagai-Braesh, J. Andrell, E. Percivalle, J. C. Sammartino, Y. Wang, S. Vlachiotis, J. Attevall, F. Bergami, A. Ferrari, , Q. Pan-Hammarstrom

This study tracks SARS-CoV-2 immunity in patients up to 15 months post-infection, showing sustained antibody and memory B/T cell responses but reduced neutralization against variants.

bioRxiv · Oct 8, 2021Immunology

Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease

R. De Gasparo, M. Pedotti, L. Simonelli, P. Nickl, F. Muecksch, I. Cassaniti, E. Percivalle, J. C. C. Lorenzi, F. Mazzola, D. Magri, T. Michalcikova, J. Haviernik, V. Honig, B. Mrazkova, N. Polakova, , T. Hatziioannou

bioRxiv · Jan 22, 2021 · PreprintImmunology

Persistence of SARS-CoV-2 specific B- and T-cell responses in convalescent COVID-19 patients 6-8 months after the infection

N. Sherina, A. Piralla, L. Du, H. Wan, M. Kumagai-Braesh, J. Andrell, S. Braesch-Andersen, I. Cassaniti, E. Percivalle, A. Sarasini, F. Bergami, R. Di Martino, M. Colaneri, M. Vecchia, M. Sambo, , Q. Pan-Hammarstrom

This study tracks SARS-CoV-2 specific B- and T-cell responses in convalescent patients 6-8 months post-infection, finding sustained memory cell responses despite declining antibody levels.

bioRxiv · Nov 6, 2020 · PreprintImmunology

Performance assessment of Respiratory Viral ELITe MGB(R) assay for the quantitative detection of influenza A/B and respiratory syncytial viruses

A. Piralla, F. Giardina, A. Fratini, D. Sapia, F. Rovida, F. Baldanti

The paper assesses the performance of a triplex PCR assay for detecting and quantifying influenza A/B and RSV, showing high agreement and correlation with in-house assays for FluA and RSV, but lower for FluB.

bioRxiv · May 14, 2020 · PreprintMicrobiology