ImmunologybioRxivPreprint
HIF-1α-mediated mitochondrial-glycolytic reprogramming controls the transition of precursor to terminally exhausted T cells
H. Wu, X. Zhao, S. M. Hochrein…·M. Vaeth
This study identifies HIF-1α-mediated metabolic reprogramming as a mechanism controlling the transition of precursor T cells to terminally exhausted T cells in chronic infections and cancer.
DOI 10.1101/2023.08.31.555662