Author

R. E. Alvarado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. L. Routh· 3 shared C. Schindewolf· 3 shared D. H. Walker· 3 shared J. A. Plante· 3 shared K. S. Plante· 3 shared S. Weaver· 3 shared V. D. Menachery· 3 shared B. A. Johnson· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

A. L. Routh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivApr 17, 2023

Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection

M. N. Vu, R. E. Alvarado, D. R. Morris…·V. D. Menachery

This study identifies the N679K mutation in Omicron variants as reducing spike protein expression and attenuating SARS-CoV-2 infection, while showing a replication advantage in the upper airway.

DOI 10.1038/s41467-026-76680-4

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivSep 26, 2022

SARS-CoV-2 Uses Nonstructural Protein 16 to Evade Restriction by IFIT1 and IFIT3

C. Schindewolf, K. Lokugamage, M. Vu…·V. D. Menachery

This paper shows that SARS-CoV-2's NSP16 protein helps evade immune detection by methylating viral mRNA, and disrupting this function reduces viral replication and disease in hamsters.

DOI 10.1128/jvi.01532-22

mouseexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivDec 15, 2021

QTQTN motif upstream of the furin-cleavage site plays key role in SARS-CoV-2 infection and pathogenesis.

M. N. Vu, K. Lokugamage, J. A. Plante…·V. D. Menachery

This study shows that deleting the QTQTN motif reduces SARS-CoV-2 replication and disease by affecting spike processing and glycosylation.

DOI 10.1073/pnas.2205690119

humanproteomics

𝕏 PostBluesky