Author

R. E. Gerszten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:metabolomics· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

X. Shi· 3 shared C. B. Clish· 2 shared J. Z. Long· 2 shared S. Deng· 2 shared U. Tahir· 2 shared V. L. Li· 2 shared W. Wei· 2 shared X. Lyu· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPhysiology

X. Shi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PhysiologybioRxivPreprintNov 2, 2023

Lac-Phe mediates the anti-obesity effect of metformin

S. Xiao, V. L. Li, X. Lyu…·J. Z. Long

This study identifies Lac-Phe as a mediator of metformin's anti-obesity effects through experiments in mice and human cohorts.

DOI 10.1101/2023.11.02.565321

𝕏 PostBluesky

BiochemistrybioRxivMar 9, 2023

CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels

J. T. Tanzo, V. L. Li, A. L. Wiggenhorn…·M. D. Benson

The paper identifies CYP4F2 as a human-specific genetic determinant of plasma N-acyl amino acid levels and shows its role in metabolic diversification.

DOI 10.1016/j.jbc.2023.104764

humanmetabolomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintFeb 1, 2022

Modeling of Alpha-1 Antitrypsin Deficiency with Syngeneic Human iPSC-Hepatocytes Reveals Metabolic Dysregulation and Cellular Heterogeneity in PiMZ and PiZZ Hepatocytes

J. Kaserman, R. B. Werder, F. Wang…·A. A. Wilson

This study uses CRISPR-Cas9 to create syngeneic iPSC-derived hepatocytes with ZAAT heterozygosity, revealing metabolic dysregulation and cellular heterogeneity in MZ and ZZ cells.

DOI 10.1101/2022.02.01.478663

𝕏 PostBluesky

PhysiologybioRxivOct 5, 2020

Metabolomic profiling identifies complex lipid species associated with response to weight loss interventions

N. A. Bihlmeyer, L. C. Kwee, C. B. Clish…·S. H. Shah

The paper identifies metabolites, particularly lipids, associated with response to weight loss interventions and highlights their role in metabolic heterogeneity.

DOI 10.1371/journal.pone.0240764

humanmetabolomics

𝕏 PostBluesky