Author

R. Ghouil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Zinn-Justin· 3 shared A.-A. Arteni· 2 shared D. Loew· 2 shared F. Dingli· 2 shared M. Ouldali· 2 shared S. Miron· 2 shared A. Alik· 1 shared A. Honfozo· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

S. Zinn-Justin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BRCA2-HSF2BP Oligomeric Ring Disassembly by BRME1 Promotes Homologous Recombination

R. Ghouil, S. Miron, K. Sato, D. Ristic, S. E. van Rossum-Fikkert, P. Legrand, M. Ouldali, J.-M. Winter, V. Ropars, G. David, A.-A. Arteni, C. Wyman, P. Knipscheer, R. Kanaar, A. N. Zelensky, S. Zinn-Justin

The paper shows that BRME1 disrupts the HSF2BP-BRCA2 ring complex, preventing BRCA2 degradation and promoting homologous recombination in meiosis.

bioRxiv · Apr 27, 2023Biochemistry

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

C. Gelot, M. T. Kovacs, S. Miron, E. Mylne, R. Ghouil, T. Popova, F. Dingli, D. Loew, J. Guirouilh-Barbat, E. Del Nery, S. Zinn-Justin, R. Ceccaldi

This study identifies Polθ as a key factor in repairing DNA double strand breaks during mitosis, showing that its phosphorylation by PLK1 enables this process and maintains genome integrity.

bioRxiv · Mar 17, 2023Cell Biology

Structural characterization of stem cell factors Oct4, Sox2, Nanog and Esrrb disordered domains, and a method to identify their phospho-dependent binding partners.

F.-X. Theillet, C. Bouguechtouli, R. Ghouil, A. Alik, F. Dingli, D. Loew

The paper structurally characterizes disordered domains of pluripotency transcription factors and presents a method to identify their phospho-dependent binding partners using NMR and proteomics.

bioRxiv · Mar 5, 2023Biochemistry

Structural analysis of Toxoplasma gondii sortilin

A. Honfozo, R. Ghouil, T. D. Alayi, M. Ouldali, A.-A. Arteni, C. M. Atindehou, L. A. Fanou, Y. Hathout, S. Zinn-Justin, S. Tomavo

This study identifies TgSORT as an essential cargo receptor in Toxoplasma gondii and presents its structural analysis using molecular modeling and electron microscopy.

bioRxiv · Nov 17, 2022 · PreprintCell Biology