BRCA2-HSF2BP Oligomeric Ring Disassembly by BRME1 Promotes Homologous Recombination
R. Ghouil, S. Miron, K. Sato…·S. Zinn-Justin
The paper shows that BRME1 disrupts the HSF2BP-BRCA2 ring complex, preventing BRCA2 degradation and promoting homologous recombination in meiosis.