MicrobiologyCell ReportsPeer-reviewed
The Achromobacter Type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes
K. Turton, H. Parks, P. Zarodkiewicz…·M. A. Valvano
This study shows Achromobacter uses its Type 3 Secretion System to trigger pyroptosis via NLRC4 and NLRP3 inflammasomes, causing immunopathology in macrophages and mice.