Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia
G. Qin, J. Dai, S. Chien…·P. S. Becker
The paper identifies mutation patterns linked to drug sensitivity in AML using integrated computational and experimental analysis.
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5 papers
Recent·Most cited
G. Qin, J. Dai, S. Chien…·P. S. Becker
The paper identifies mutation patterns linked to drug sensitivity in AML using integrated computational and experimental analysis.
H. T. Nguyen, W. Tang, A. L. H. Webster…·R. J. Monnat
The paper develops isogenic head and neck cancer cell line pairs to study Fanconi anemia-associated cancers and their treatment.
A. D. Rodriguez, L. F. Horowitz, K. Castro…·A. Folch
This paper develops a microfluidic platform for testing cancer drugs on intact tumor slices to improve drug response assessment in precision oncology.
L. F. Horowitz, A. D. Rodriguez, Z. Dereli-Korkut…·R. C. Rostomily
This paper develops a microfluidic platform for rapid, multiplexed drug testing of cancer slices to guide personalized therapy.
E. Juarez, N. Chambwe, W. Tang…·A. McCullough
The paper identifies DNA damage repair pathways that reduce formaldehyde toxicity in human cell lines and shows their conservation in budding yeast.