PhysiologybioRxiv
Beta-cell adaptation to metabolic stresses requires prolactin receptor signaling
D. Lee, R. Kahlon, D. Kola-Ilesanmi…·C. Huang
This study shows that prolactin receptor signaling protects beta-cells from metabolic stress by maintaining incretin receptor expression and insulin secretion.
DOI 10.1152/ajpendo.00108.2025