Author

R. Lucas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. C. Pike· 1 shared A. Chu· 1 shared A. Das· 1 shared A. Prakash· 1 shared A. Sajid· 1 shared B. G. Davis· 1 shared C. E. Barry· 1 shared C. V. Robinson· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBiochemistry

A. C. Pike

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Endothelial Drp1 Couples VEGF-induced Redox Signaling with Glycolysis Through Cysteine Oxidation to Drive Angiogenesis

S. Nagarkoti, Y.-M. Kim, A. Das, D. Ash, E. A. Vitriol, T.-A. Read, V. Sudhahar, M. S. Hossain, S. Yadav, M. McMenamin, S. Kelley, R. Lucas, D. W. A. Stepp, E. J. Belin de Chantemele, R. B. Caldwell, , M. Ushio-Fukai

bioRxiv · Jun 15, 2024 · PreprintCell Biology

Mitochondrial genome variation affects humoral and cell-mediated innate immune responses and infection outcomes

T. S. Salminen, L. Vesala, Y. Basikhina, M. Kutzer, T. Tuomela, R. Lucas, K. Monteith, A. Prakash, T. Tietz, P. F. Vale

This study shows that mitochondrial DNA variation influences innate immune responses and infection outcomes in Drosophila by affecting gene expression and immune cell function.

bioRxiv · Mar 28, 2024 · PreprintImmunology

Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design

Y. Y. Dong, H. Wang, A. C. Pike, S. J. Cochrane, S. Hamedzade, F. J. Wyszynsk, S. R. Bushell, S. F. Royer, D. A. Widdick, A. Sajid, H. I. Boshoff, R. Lucas, W.-M. Liu, S. S. Lee, T. Machida, , E. P. Carpenter

This paper determines the structures of DPAGT1 with substrates and inhibitors, revealing catalytic mechanisms and disease-causing mutations, and designs non-toxic antibiotics for tuberculosis.

bioRxiv · Apr 2, 2018Biochemistry