BiochemistrybioRxivPreprint
A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^LL cleavage occurs first and there is no CaaX processing by ZMPSTE24
L. Nie, E. Spear, T. D. Babatz…·E. P. Carpenter
This study challenges the established order of prelamin A processing by ZMPSTE24, showing that SY^LL cleavage occurs first and independently of C-terminal modifications.
DOI 10.1101/2020.05.13.093849