PhysiologybioRxivPreprint
Reconstitution of the host holobiont in germ-free rats acutely increases bone growth and affects marrow cellular content
P. J. Czernik, R. M. Golonka, S. Chakraborty…·B. Lecka-Czernik
This study shows that reconstituting the gut microbiota in germ-free rats accelerates bone growth and alters marrow cell composition, with effects linked to increased short-chain fatty acids and IGF-1 levels.
DOI 10.1101/2020.07.15.201657