BiochemistrybioRxivPreprint
Identification of extracellular membrane protein ENPP3 as a major cGAMP hydrolase, cementing cGAMP's role as an immunotransmitter
R. Mardjuki, S. Wang, J. Carozza…·L. Li
The paper identifies ENPP3 as a second cGAMP hydrolase, showing it regulates cGAMP levels and impacts cancer immunity.
DOI 10.1101/2024.01.12.575449