Author

R. Matthiesen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Pathology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. S. Carvalho· 2 shared C. Klose· 2 shared H. C. Beck· 2 shared J. Ferreira· 2 shared J. Sampaio· 2 shared K. Simons· 2 shared N. Domingues· 2 shared O. V. Vieira· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. S. Carvalho

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causes in vitro and in vivo Inflammation

N. Domingues, J. Gaifem, R. Matthiesen, D. Saraiva, L. Bento, A. Marques, I. Soares, J. Sampaio, C. Klose, M. Surma, M. Almeida, G. Mendes, P. Goncalves, J. Ferreira, R. Gouveia e Melo, , O. V. Vieira

The paper identifies cholesteryl hemiazelate (ChA) as an oxidized lipid that induces inflammation in vitro and in vivo, contributing to atherosclerosis.

bioRxiv · Feb 9, 2023 · PreprintPathology

LAMP2A regulates the loading of proteins into exosomes.

J. V. Ferreira, A. da Rosa Soares, J. S. Ramalho, C. M. Carvalho, M. H. Cardoso, P. Pintado, A. S. Carvalho, H. C. Beck, R. Matthiesen, M. Zuzarte, H. Girao, G. van Niel, P. Pereira

The paper identifies LAMP2A as a key regulator of protein loading into exosomes, independent of ESCRT machinery, and demonstrates its role in transporting hypoxia signals via exosomes.

bioRxiv · Jul 26, 2021Cell Biology

Messages From the Small Intestine Carried by Extracellular Vesicles in Prediabetes: a Proteomic Portrait

I. Ferreira, R. M. de Oliveira, A. S. Carvalho, A. Teshima, H. C. Beck, R. Matthiesen, B. C. Silva, M. P. Macedo

This study identifies changes in the proteome of gut-derived extracellular vesicles in prediabetic mice, showing altered protein packaging that may transmit metabolic signals to other tissues.

bioRxiv · Feb 19, 2021Pathology

Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages

N. Domingues, R. D. A. Calado, P. Brito, R. Matthiesen, J. Ramalho, M. I. L. Soares, T. Pereira, L. Oliveira, J. Vicente, L. H. Wong, S. M. Cho, I. Simoes, J. Sampaio, C. Klose, M. A. Surma, , O. V. Vieira

This study identifies cholesteryl hemiazelate as a cause of lysosome dysfunction and exocytosis in macrophages, contributing to atherosclerosis.

bioRxiv · Jan 5, 2021 · PreprintCell Biology