Author

P. Goncalves

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Ecology· 1 Immunology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 4 Approach:statistical model· 4 Approach:experimental assay· 3 Assay:whole-genome sequencing· 3 Organism:yeast· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2

Frequent Co-Authors

A. B. Hulfachor· 2 shared C. Goncalves· 2 shared C. T. Hittinger· 2 shared D. A. Opulente· 2 shared D. Libkind· 2 shared E. J. Ubbelohde· 2 shared J. Kominek· 2 shared J. P. Sampaio· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersEvolutionary Biology

A. B. Hulfachor

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Author profile →

6 papers

Recent·Most cited

A comprehensive evaluation of taxonomic classifiers in marine vertebrate eDNA studies

P. E. Bayer, A. Bennett, G. Nester, S. Corrigan, E. J. Raes, A. S. McInnes, M. Cooper, M. E. Ayad, P. McVey, A. Kardailsky, J. Pearce, M. W. Fraser, P. Goncalves, S. Burnell, S. Rauschert

This study evaluates nine taxonomic classifiers for marine vertebrate eDNA studies, finding MMSeqs2 and Metabuli outperform BLAST in accuracy and reducing false positives.

bioRxiv · Feb 15, 2024Ecology

Genomic and ecological factors shaping specialism and generalism across an entire subphylum

D. A. Opulente, A. L. LaBella, M.-C. Harrison, J. F. Wolters, C. Liu, Y. Li, J. Kominek, J. L. Steenwyk, H. R. Stoneman, J. VanDenAvond, C. R. Miller, Q. K. Langdon, M. Silva, C. Goncalves, E. J. Ubbelohde, , C. T. Hittinger

The paper analyzes genomic, metabolic, and ecological data from nearly all Saccharomycotina yeast species to show that intrinsic genetic factors, not trade-offs or extrinsic factors, drive variation in niche breadth.

bioRxiv · Jun 19, 2023 · PreprintEvolutionary Biology

Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causes in vitro and in vivo Inflammation

N. Domingues, J. Gaifem, R. Matthiesen, D. Saraiva, L. Bento, A. Marques, I. Soares, J. Sampaio, C. Klose, M. Surma, M. Almeida, G. Mendes, P. Goncalves, J. Ferreira, R. Gouveia e Melo, , O. V. Vieira

The paper identifies cholesteryl hemiazelate (ChA) as an oxidized lipid that induces inflammation in vitro and in vivo, contributing to atherosclerosis.

bioRxiv · Feb 9, 2023 · PreprintPathology

Macroevolutionary diversity of traits and genomes in the model yeast genus Saccharomyces

D. Peris, E. J. Ubbelohde, M. C. Kuang, J. Kominek, Q. K. Langdon, M. Adams, J. A. Koshalek, A. B. Hulfachor, D. A. Opulente, D. J. Hall, K. Hyma, J. C. Fay, J.-B. Leducq, G. Charron, C. R. Landry, , C. T. Hittinger

The paper studies genetic and phenotypic diversity across 1,800 Saccharomyces strains, revealing insights into macroevolutionary processes and gene flow effects on traits.

bioRxiv · Mar 30, 2022Evolutionary Biology

A monocyte/dendritic cell molecular signature of SARS-CoV2-related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis

C. de Cevins, M. Luka, N. Smith, S. Meynier, A. Magerus, F. Carbone, V. Garcia Paredes, L. Barnabei, M. Batignes, A. Boulle, M.-C. Stolzenberg, B. P. Perot, B. Charbit, T. Fali, V. Pirabarakan, , Gras Leguen

The paper identifies a monocyte/dendritic cell gene signature in severe MIS-C with myocarditis, linked to NF-κB activity and cytokine signaling.

bioRxiv · Feb 23, 2021Immunology

Multiple pathways to homothallism in closely related yeast lineages in the Basidiomycota

A. Cabrita, M. David-Palma, P. H. Brito, J. Heitman, M. A. Coelho, P. Goncalves

This study identifies distinct molecular mechanisms of homothallism in two closely related yeast species, suggesting independent evolution of this trait within the Cystofilobasidiales lineage.

bioRxiv · Sep 30, 2020Microbiology