The Intestine is a Major Contributor to Circulating TCA Cycle Intermediates in Mice
W. Tong, S. A. Hannou, Y. Wang, I. Astapova, A. Sargsyan, R. Monn, V. Thiriveedi, D. Li, J. R. McCann, J. F. Rawls, J. Roper, G.-F. Zhang, M. A. Herman
This study identifies the intestine as the primary source of circulating TCA cycle intermediates in mice, showing endogenous production exceeds microbial contributions.
bioRxiv · Jan 20, 2022Physiology