Cancer BiologybioRxiv
Respiratory Complex I Regulates Dendritic Cell Maturation in Explant Model of Human Tumor Immune Microenvironment
R. Turpin, R. Liu, P. Munne…·J. Klefstrom
The paper uses a patient-derived explant model to show metformin enhances dendritic cell maturation by inhibiting complex I, improving anti-tumor immunity when combined with venetoclax.
DOI 10.1136/jitc-2023-008053