BioengineeringbioRxiv
Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library
T. Ej Efternavn, R. W. Pedersen, C. Rimbault…·A. H. Laustsen
The paper discovers a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library without histidine doping, showing that pH-dependency can arise without histidine residues.
DOI 10.1002/pro.4821